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1

Vision in Children and Adolescents with Autistic Spectrum Disorder: Evidence for Reduced Convergence

Elizabeth Milne, Helen Griffiths, David Buckley, Alison Scope

Journal:

Journal of Autism and Developmental Disorders

Year:

2009

Language:

english

File:

PDF, 295 KB

english, 2009

2

4-[(Alkylamino)methyl]furo[3,2-c]pyridines: A New Series of Selective .kappa.-Receptor Agonists

Naylor, Alan, Judd, Duncan B., Scopes, David I. C., Hayes, Ann G., Birch, Philip J.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 785 KB

english, 1994

3

Evolution of a Novel Series of [(N,N-Dimethylamino)propyl]- and Piperazinylbenzanilides as the First Selective 5-HT1D Antagonists

Clitherow, John W., Scopes, David I. C., Skingle, Malcolm, Jordan, Christopher C., Feniuk, Wasyl, Campbell, Ian B., Carter, Malcolm C., Collington, Eric W., Connor, Helen E.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 437 KB

english, 1994

4

Development of Louth flood alleviation scheme outline design

Journal:

Dams and Reservoirs

Year:

2015

Language:

english

File:

PDF, 921 KB

english, 2015

5

A Convenient Route to Imino Sugars and Analogues of Siastatin B (X).

Nicola J. Birch, Phillip J. Parsons, David I. C. Scopes

Journal:

Year:

2005

File:

PDF, 25 KB

2005

6

Rapid purification of yeast alcohol dehydrogenase

Robert K. Scopes, Kerry Griffiths-Smith, David G. Millar

Journal:

Analytical Biochemistry

Year:

1981

Language:

english

File:

PDF, 164 KB

english, 1981

7

Coupling-elimination reactions of 2,5-anhydro-3,4,6-tri-O-benzoyl-d-allonic acid: synthesis of 2′-deoxyribo-C-nucleosides

Lars J.S. Knutsen, Roger F. Newton, David I.C. Scopes, Graham Klinkert

Journal:

Carbohydrate Research

Year:

1982

Language:

english

File:

PDF, 194 KB

english, 1982

8

A novel series of arylpiperazines with high affinity and selectivity for the dopamine D3 receptor

P. John Murray, Lee A. Harrison, Martin R. Johnson, Graeme M. Robertson, David I.C. Scopes, David R. Bull, Elizabeth A. Graham, Ann G. Hayes, Gavin J. Kilpatrick, Izaak Den Daas, Charles Large, Michae

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 210 KB

english, 1995

9

Rhodanine-3-acetic acid derivatives as inhibitors of fungal protein mannosyl transferase 1 (PMT1)

Michael G Orchard, Judi C Neuss, Carl M.S Galley, Andrew Carr, David W Porter, Phillip Smith, David I.C Scopes, David Haydon, Katherine Vousden, Colin R Stubberfield, Kate Young, Martin Page

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

10

Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor

Stephen M. Courtney, Philip A. Hay, Richard T. Buck, Claire S. Colville, David J. Phillips, David I.C. Scopes, Faye C. Pollard, Martin J. Page, James M. Bennett, Margaret L. Hircock, Edward A. McKenzi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 129 KB

english, 2005

11

Chiral synthesis of 6,7-benzomorphans: Synthesis of (−)1(S),2(S),4(R),6(R)-1,2,3,4,5,6-hexahydro-2,6-methano-8-methoxy -1,3,4,6-tetramethyl-3-benzazocine through the chromium hexacarbonyl mediated cyclisation of 1(S),1′(R)-1,2-dihydro-7-methoxy-1,4-dimethyl -1(N-methyl-N-trifluoroacetamido-1′-methylethan-2′-yl)naphthalene

Malcolm Sainsbury, Mary F. Mahon, Colin S. Williams, Alan Naylor, David I.C. Scopes

Journal:

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

12

Photolytic ring-expansions of 6-azidoquinolines and 6-azidodiazines: some unexpected azepine ring-opening reactions

Roy Hayes, Joseph M. Schofield, Robert K. Smalley, David I.C. Scopes

Journal:

Year:

1990

Language:

english

File:

PDF, 546 KB

english, 1990

13

The syntheses of polycyclic molecules containing b-carboline units by the photochemically induced ring closure of enamides

Michael Hutchins, Malcolm Sainsbury, David Scopes

Journal:

Year:

1984

Language:

english

File:

PDF, 268 KB

english, 1984

14

Substitution and addition reactions of isoindoles

Raymond Bonnett, Stephanie A. North, Roger F. Newton, David I.C. Scopes

Journal:

Year:

1983

Language:

english

File:

PDF, 466 KB

english, 1983

15

Beckman cleavage of 1,2,3,4,5,6-hexahydro-3,6-dimethyl-2,6-methano-3-benzazocin-11-one oxime (2,5-dimethyl-9-oxo-6,7-benzomorphan oxime); a new route to 3-benzazocines

Brian Iddon, Donald Price, Hans Suschitzky, David I.C. Scopes

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 236 KB

english, 1983

16

An enantioselective synthesis of a 6,7-bentzomorphan through the cyclisation of the chromium tricarbonyl complex of an 1-(aminoethan-2′-yl)- 1,2-dihydronaphthalene

Malcolm Sainsbury, Colin S. Williams, Alan Naylor, David I.C. Scopes

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 230 KB

english, 1990

17

The preparation of novel dopamine analogues via palladium catalysed cyclisation reactions

Antony J. Davies, Richard J.K. Taylor, David I. Scopes, Alan H. Wadsworth

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 240 KB

english, 1992

18

A technique for studying the biological efficiency of small droplets of pesticide solutions and a consideration of the implications

David C. Munthali, Nigel E. A. Scopes

Journal:

Pest Management Science

Year:

1982

Language:

english

File:

PDF, 210 KB

english, 1982

19

Activity and stability of glycolytic enzymes in the presence of ethanol

David G. Millar, Kerry Griffiths-Smith, Elizabeth Algar, Robert K. Scopes

Journal:

Biotechnology Letters

Year:

1982

Language:

english

File:

PDF, 377 KB

english, 1982

20

Identification of an intronic regulatory element in the human protein C (PROC) gene

Monee Shamsher, Nadia Chuzhanova, Brad Friedman, Deborah Scopes, Anwar Alhaq, David Millar, David Cooper, Lutz-Peter Berg

Journal:

Year:

2000

Language:

english

File:

PDF, 189 KB

english, 2000

21

2,3-Dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid derivatives: a novel class of small molecule heparanase inhibitors

Stephen M. Courtney, Philip A. Hay, Richard T. Buck, Claire S. Colville, David W. Porter, David I.C. Scopes, Faye C. Pollard, Martin J. Page, James M. Bennett, Margaret L. Hircock, Edward A. McKenzie,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 268 KB

english, 2004

22

Alternative routes for the genesis of kinetin: A synthetic intramolecular route from 2′-deoxyadenosine to kinetin

David I.C. Scopes, Ewe Zarnack, Nelson J. Leonard, Ruth Y. Scmith, Folke Skoog

Journal:

Year:

1976

Language:

english

File:

PDF, 521 KB

english, 1976

23

White Globules in Melanocytic Neoplasms: In Vivo and Ex Vivo Characteristics

Natalia Jaimes, Alon Scope, Julia Welzel, Katie X. Wang, David A. Lee, Daniel M. Siegel, Ashfaq A. Marghoob

Journal:

Dermatologic Surgery

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

24

Synthesis of C-nucleoside isosteres of 9-(2-hydroxyethoxymethyl)guanine (acyclovir)

William L. Mitchell, Malcolm L. Hill, Roger F. Newton, Paul Ravenscroft, David I. C. Scopes

Journal:

Journal of Heterocyclic Chemistry

Year:

1984

File:

PDF, 261 KB

1984

25

Kinetic analysis of the activation of Zymomonas mobilis glucokinase by phosphate

Robert K. Scopes, David R. Bannon

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1995

Language:

english

File:

PDF, 592 KB

english, 1995

26

Human Hexose-6-phosphate Dehydrogenase (Glucose 1-Dehydrogenase) Encoded at 1p36: Coding Sequence and Expression

Philip J. Mason, David Stevens, Amalia Diez, Stuart W. Knight, Deborah A. Scopes, Tom J. Vulliamy

Journal:

Blood Cells, Molecules, and Diseases

Year:

1999

Language:

english

File:

PDF, 170 KB

english, 1999

27

Characterisation of the specific binding of the histamine H3 receptor antagonist radioligand [3H]GR168320

Jason D. Brown, Celestine T. O'Shaughnessy, Gavin J. Kilpatrick, David I.C. Scopes, Paul Beswick, John W. Clitherow, Julie C. Barnes

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 560 KB

english, 1996

28

RS-0406 Arrests Amyloid-β Oligomer-Induced Behavioural Deterioration In Vivo

Eugene O’Hare, David I.C. Scopes, J. Mark Treherne, Kelly Norwood, David Spanswick, Eun-Mee Kim

Journal:

Behavioural Brain Research

Year:

2010

Language:

english

File:

PDF, 709 KB

english, 2010

29

Enantiomerically pure amines by a new method: biotransformation of oxalamic esters using the lipase from Candida antarctica

Chapman, Daniel T., Crout, David H. G., Mahmoudian, Mahmoud, Scopes, David I. C., Smith, Paul W.

Journal:

Chemical Communications

Year:

1996

Language:

english

File:

PDF, 181 KB

english, 1996

30

Synthesis, antinociceptive activity and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols

Judd, Duncan B., Brown, Dearg S., Lloyd, Jane E., McElroy, Andrew B., Scopes, David I. C., Birch, Phillip J., Hayes, Ann G., Sheehan, Michael J.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.12 MB

english, 1992

31

Synthesis and reactions of 1,2,3,4,5,6-hexahydro-3,6-dimethyl-2,6-methano-3-benzazocin-11-one (2,5-dimethyl-9-oxo-6,7-benzomorphan); a new route to 3-benzazocines

Iddon, Brian, Price, Donald, Suschitzky, Hans, Scopes, David I. C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1983

Language:

english

File:

PDF, 1.66 MB

english, 1983

32

New .kappa.-receptor agonists based upon a 2-[(alkylamino)methyl]piperidine nucleus

Scopes, David I. C., Hayes, Norman F., Bays, David E., Belton, David, Brain, John, Brown, Dearg S., Judd, Duncan B., McElroy, Andrew B., Meerholz, Clive A.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.63 MB

english, 1992

33

Synthesis of carbocyclic C-nucleoside analogues from 8,9,10-trinorborn-5-en-2-ol

Cookson, Richard C., Dudfield, Philip J., Scopes, David I. C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1986

Language:

english

File:

PDF, 762 KB

english, 1986

34

Synthesis, antinociceptive activity and opioid receptor profiles of trans-3-(octahydro-2H-pyrano[2,3-c]pyridin-4a-yl)phenols and trans-3-(octahydro-1H-pyrano[3,4-c]pyridin-4a-yl)phenols

Bays, David E., Brown, Dearg S., Lloyd, Jane E., McElroy, Andrew B., Scopes, David I. C., Birch, Phillip J., Hayes, Ann G., Sheehan, Michael J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1989

Language:

english

File:

PDF, 1.87 MB

english, 1989

35

Independent Component Analysis Reveals Atypical Electroencephalographic Activity During Visual Perception in Individuals with Autism

Elizabeth Milne, Alison Scope, Olivier Pascalis, David Buckley, Scott Makeig

Journal:

Biological Psychiatry

Year:

2009

Language:

english

File:

PDF, 4.56 MB

english, 2009

36

Bromobenzofuran-Based Non-peptide Antagonists of Angiotensin II: GR138950, a Potent Antihypertensive Agent with High Oral Bioavailability

Judd, Duncan B., Dowle, Michael D., Middlemiss, David, Scopes, David I. C., Ross, Barry C., Jack, Torquil I., Pass, Martin, Tranquillini, Elvira, Hobson, Julie E.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.58 MB

english, 1994

37

Azabenzocycloheptenones. Part 20. Synthesis and utilisation of 4-amino-1,2,3,4-tetrahydro-1(1H)-benzazepines

Booker-Milburn, Kevin I., Dunkin, Ian R., Kelly, Frances C., Khalaf, Abedawn I., Learmonth, David A., Proctor, George R., Scopes, David I. C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1997

Language:

english

File:

PDF, 215 KB

english, 1997

38

Synthesis and antiviral properties of 5-(2-substituted vinyl)-6-aza-2'-deoxyuridines

Mitchell, William L., Ravenscroft, Paul, Hill, Malcolm L., Knutsen, Lars J. S., Judkins, Brian D., Newton, Roger F., Scopes, David I. C.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 1.09 MB

english, 1986

39

A potent new class of .kappa.-receptor agonist: 4-substituted 1-(arylacetyl)-2-[(dialkylamino)methyl]piperazines

Naylor, Alan, Judd, Duncan B., Lloyd, Jane E., Scopes, David I. C., Hayes, Ann G., Birch, Philip J.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 2.00 MB

english, 1993

40

Bicyclic heterocycles with nitrogen at the ring junction. Part 2. Application of the Dakin?West reaction to the synthesis of imidazo[5,1-f]-1,2,4-triazin-4(3H)-ones

Charles, Isabel, Latham, David W. S., Hartley, David, Oxford, Alexander W., Scopes, David I. C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1980

Language:

english

File:

PDF, 868 KB

english, 1980

41

Synthesis of imidazo-fused bridgehead-nitrogen C-nucleosides via dehydrative coupling reactions of 2,5-anhydro-3,4,6-tri-O-benzoyl-D-allonic acid

Knutsen, Lars J. S., Judkins, Brian D., Mitchell, William L., Newton, Roger F., Scopes, David I. C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 1.23 MB

english, 1984

42

Studies in .beta.-lactams. 5. Enolate amination with O-mesitylenesulfonylhydroxylamine

Scopes, David I. C., Kluge, Arthur F., Edwards, John A.

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 301 KB

english, 1977

43

The N-Methylated Peptide SEN304 Powerfully Inhibits Aβ(1–42) Toxicity by Perturbing Oligomer Formation

Amijee, Hozefa, Bate, Clive, Williams, Alun, Virdee, Jasmeet, Jeggo, Ross, Spanswick, David, Scopes, David I.C., Treherne, J. Mark, Mazzitelli, Sonia, Chawner, Ross, Eyers, Claire E., Doig, Andrew J.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.05 MB

english, 2012

44

Glyco- and Peptidomimetics from Three-Component Joullié−Ugi Coupling Show Selective Antiviral Activity

Chapman, Timothy M., Davies, Ieuan G., Gu, Baohua, Block, Timothy M., Scopes, David I. C., Hay, Philip A., Courtney, Stephen M., McNeill, Luke A., Schofield, Christopher J., Davis, Benjamin G.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 79 KB

english, 2005

45

Orally bioavailable small molecule drug protects memory in Alzheimer's disease models

O'Hare, Eugene, Scopes, David I.C., Kim, Eun-Mee, Palmer, Philip, Jones, Martyn, Whyment, Andrew D., Spanswick, David, Amijee, Hozefa, Nerou, Edmund, McMahon, Bridgeen, Treherne, J. Mark, Jeggo, Ross

Journal:

Neurobiology of Aging

Year:

2013

Language:

english

File:

PDF, 970 KB

english, 2013

46

In Vivo Drug Screening in C.Elegans Identifies Novel Compounds that Inhibit Aβ1-42 Toxicity

Sattelle, David B., Fraboulet, Sandrine, Moloney, Aileen M., Nussher, Anja, Jones, Andrew K., Buckingham, Stephen D., Amijee, Hozefa, Scopes, David I.C., Treherne, Mark, Link, Christopher D.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 45 KB

english, 2010

47

P4-300

Doig, Andrew, Kokkoni, Nicoleta, Stott, Kelvin, Amijee, Hozefa, Bottomley, Joanna, Mason, Jody, Treherne, Mark, Scopes, David

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

48

Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500

Lo, Adrian C., Tesseur, Ina, Scopes, David I.C., Nerou, Edmund, Callaerts-Vegh, Zsuzsanna, Vermaercke, Ben, Treherne, J. Mark, De Strooper, Bart, D'Hooge, Rudi

Journal:

Neuropharmacology

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

49

P2-295: β-amyloid aggregation inhibitors for the treatment of Alzheimer's disease

Doig, Andrew J., Amijee, Hozefa, Scopes, David I.C., Treherne, J. Mark

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

50

P2-358: SEN1269: A novel inhibitor of amyloid-beta toxicity

Scopes, David I., Amijee, Hozefa, Nerou, Edmund, Treherne, Mark, O'Hare, Eugene, Jeggo, Ross, Whyment, Andrew, Spanswick, David

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 74 KB

english, 2008

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